Country of residence
Department of Pharmaceutics, Kwame Nkrumah University of Science and Technology
Current Research Areas Infectious diseases are one of the leading causes of morbidity and mortality in the developing countries. In Africa and other developing countries including Ghana, it is estimated that 70 to 80% of patients rely on traditional medicine for their health needs including treatment of infectious diseases. This is because of the high cost of orthodox medicines as well as inadequate healthcare facilities and professionals, while herbal medicines are much more easily available and affordable (sometimes free of charge) from traditional healers. Thus, African folk medicine offers a vast repository of plants and herbal preparations with documented usefulness against infections, many of which still await chemical investigation and possible formulation into suitable dosage forms. Medicinal plants are therefore being investigated for their potential to treat infectious diseases including neglected diseases such as Leishmania major, Onchocerca volvulus, Schistosoma sp and Onchocerca ochengi and below are my major areas:
* Search for bioactive compounds from medicinal plants against Leishmania major, Onchocerca volvulu, Schistosoma sp and Onchocerca ochengi (neglected diseases).
* Wound healing activities of some isolated compounds and extracts from medicinal plants
* Search for antimicrobial agents from medicinal plants
* Antibiotic resistance in humans, poultry and other animals
1. Agyare, C., Dwobeng, A.S., Agyepong, N., Boakye, Y.D., Mensah, B.K., Ayande, P.G., Adarkwa-Yiadom, M. (2013). Antimicrobial, antioxidant, and wound healing properties of Kigelia africana (Lam.) Beneth. and Strophanthus hispidus DC. Advances in Pharmacological Sciences, Article ID 692613, 10 pages. doi.org/10.1155/2013/692613.
2. Saana, S.B.B.M., Adu, F., Agyare, C., Gbedema, S.Y. Antibiotic resistance patterns of strains of Staphylococcus aureus isolated from patients in three hospitals in Kumasi, Ghana. Journal of Bacteriology Research, 5(3):35-40. doi:10.5897/JBR2012.0081.
3. Agyare, C., Koffour, G.A., Boakye, Y.D., Mensah, K.B. (2013). Antimicrobial and anti-inflammatory properties of Funtumia elastica. Pharmaceutical Biology, 51(4):418-25. doi:10.3109/13880209.2012.738330.
4. George, D.F., Gbedema, S.Y., Agyare, C., Adu, F., Boamah, V.E., Tawiah, A.A., Saana, S.B.B.M. (2012). Antibiotic resistance patterns of Escherichia coli isolates from hospitals in Kumasi, Ghana. ISRN Microbiology, vol. 2012, Article ID 658470, 5 pages, 2012. doi:10.5402/2012/658470.
5. Ndjonka, D., Bergmann, B., Agyare, C., Zimbres F.M., Luersen, K., Hensel, A., Wrenger, C., Liebau, E. (2012). In vitro activity of extracts and isolated polyphenols from West African medicinal plants against Plasmodium falciparum. Parasitology Research, 111:827-34. DOI: 10.1007/s00436-012-2905-y.
6. Agyare, C., Koffuor, G.A., Boamah, V.E., Adu, F., Mensah, K.B., Adu-Amoah, L. (2012). Antimicrobial and anti-inflammatory activities of Pterygota macrocarpa and Cola gigantea (Sterculiaceae). Journal of Evidence-Based Complementary and Alternative Medicine, Article ID 902394, 9 pages. DOI:10.1155/2012/902394.
7. Agyare, C., Lechtenberg, M., Hensel, A. (2011). Composition of polysaccharides from aqueous extracts of some wound healing plants. Planta Medica, 77:1339-1422.